WELCOME! to my home page:
MY C.V./RESUME:
Department of Entomology, Texas A&M University, College Station, Texas, USA
eMail: begumkhurshida@yahoo.com
MY URLs: http://myprofile.cos.com/begumk
http://publicationslist.org/begumk
EDUCATION:
2003 : Ph.D., (Biopharmaceutical Sciences), Okayama University, Japan.
1999-2000: Graduate research studies, Okayama University, Japan.
1992: M.Sc. Zoology/Parasitology, Eden College/University of Dhaka, Bangladesh.
1990: B.Sc. Hons., Zoology, Eden College/University of Dhaka, Bangladesh
M.Sc. THESIS: Studies on the parasito-fauna of elasmobranch fishes in the Bay of Bengal. Eden Mohila College, University of Dhaka, Bangladesh, 1992. Supervisors: Professors A. Khatun, PhD and Joseph D'Silva, PhD.
Ph.D. THESIS: Investigations of new and potent anti-malarial drugs against malaria parasite, Plasmodium falciparum (PhD thesis, March 2003). Okayama University, Japan. Supervisor: Professor Y. Wataya, PhD.
Awords/scholarship/honors:
CAREER:
Postdoc Research Associate, Texas A&M University, USA-2008-Present
Postdoc Scholar, Molecular Physilogy Lab., Department of Entomology, Kansas State University, USA. July, 2003-2008.
Researcher, Faculty of Pharmaceutical Sciences, Okayama University, Japan; May 1999-Mar 2000.
Lecturer in Zoology, Rajuk Uttara Model College, Dhaka, Bangladesh; April 1995-April 1998.
Class Teacher of Biology, Shikkangon Pre-Cadet and High School, Dhaka, Bangladesh; Jan 1994-Mar 1995.
Research fellow, Eden College, University of Dhaka, Bangladesh; Jan 1990-Dec 1992.
Techiniques learned/used in my research:
1. Cell Culture;
a. Plasmodium falciparum (malaria parasite)
b. FM3A cell (Mouse Tumor cell)
c. S2 Cell (Drosophila embryonic cell)
2. SDS-PAGE
3. PFGE (Pulsed Field Gel Electrophoresis)
4. In Situ Hybridization
5. Flourescence in situ hybridization (FISH)
6. Southern blotting
7. Northen blotting
8. Western blotting
9. Immunohistochemistry
10. Cloning/ligation/transfection/restriction enzyme
digestion etc.
11. PCR, RT-PCR
12. Screening of drug for sensitivity (IC50, IC90)
13. Drug combinations and interactions
14. Action mechanism of antimalarial drug;
a)Hemoglobin degradation pathways
b)Hem detoxification pathways
15. Analysis of multi-drug resistant (mdr) mechanism
16. Microscopy
17. Synchronization of parasite
18. MPN method
19. Analyses of parasite recrudescence after drug treatment,
20. BAC and cDNA library screening etc.
LIST OF SCIENTIFIC PUBLICATION:
Mutti NS, Louis J, Pappan LK, Pappan K, Begum K, Chen MS,Park Y, Dittmer N, Marshall J, Reese JC, and GR Reeck (2008) A protein from the salivary glands of the pea aphid, Acyrthosiphon pisum, is essential in feeding on a n pisum, is essential in feeding on a host plant., Proc Natl Acad Sci U S A ., 105 (29), 9965-9969
Aikins MJ, Schooley D, Begum K, Dupriez V, Beeman R, and Park Y. (2008) Vasopressin like peptide and its receptor function in indirect diuretic signaling pathway in red flour beetle., Insect Biochemistry and Molecular Biology, 38 (7), 740- 748
Begum K, and Park Y. 2007. Characterization of ion transport peptide in Drosophila and Anophelis moqquito. (in preparation).
Park Y, Begum K, Kim H, and Adam M. 2007. A novel function of ion transport peptide in Drosophila ecdysis. (in preparation)
Aikins MJ, Begum K, Brown S, Beeman R and Park Y. 2006. The arginine vasopressin-like peptide and the vesipressin receptor in Tribulium castanium (in preparation).
Mutti N, Begum K, Park Y, Reese J, Reeck G, et al. 2007. Molecular characterization of a novel gene from pea aphid salivary gland. (in preparation)
Begum K, Kim H.-S. and Wataya Y. 2007. Stage specific parasite recrudescence after treatment with artemisinin.(submitted).
| 1: | Hirai S, Kikuchi H, Kim HS, Begum K, Wataya Y, Tasaka H, Miyazawa Y, Yamamoto K, Oshima Y. | Related Articles, Links |
 | Metabolites of febrifugine and its synthetic analogue by mouse liver S9 and their antimalarial activity against Plasmodium malaria parasite. J Med Chem. 2003 Sep 25;46(20):4351-9. PMID: 13678413 [PubMed - indexed for MEDLINE] | |
| 2: | Tokuyasu T, Kunikawa S, Abe M, Masuyama A, Nojima M, Kim HS, Begum K, Wataya Y. | Related Articles, Links |
| Synthesis of antimalarial yingzhaosu A analogues by the peroxidation of dienes with Co(II)/O2/Et3SiH. J Org Chem. 2003 Sep 19;68(19):7361-7. PMID: 12968887 [PubMed - indexed for MEDLINE] | |
| 3: | Begum K, Kim HS, Okuda Y, Wataya Y, Kimura M, Huruta T. | Related Articles, Links |
| Genomic analysis of mefloquine-resistant Plasmodium falciparum. Nucleic Acids Res Suppl. 2002;(2):223-4. PMID: 12903186 [PubMed - indexed for MEDLINE] | |
| 4: | Kim HS, Okuda Y, Begum K, Nagai Y, Wataya Y, Kimura M, Huruta T. | Related Articles, Links |
| Analysis of Pfmdr 1 gene in mefloquine-resistant Plasmodium falciparum. Nucleic Acids Res Suppl. 2001;(1):231-2. PMID: 12836349 [PubMed - indexed for MEDLINE] | |
| 5: | Begum K, Kim HS, Kumar V, Stojiljkovic I, Wataya Y. | Related Articles, Links |
| In vitro antimalarial activity of metalloporphyrins against Plasmodium falciparum. Parasitol Res. 2003 Jun;90(3):221-4. Epub 2003 Mar 12. PMID: 12783311 [PubMed - indexed for MEDLINE] | |
| 6: | Tran QL, Tezuka Y, Ueda JY, Nguyen NT, Maruyama Y, Begum K, Kim HS, Wataya Y, Tran QK, Kadota S. | Related Articles, Links |
| In vitro antiplasmodial activity of antimalarial medicinal plants used in Vietnamese traditional medicine. J Ethnopharmacol. 2003 Jun;86(2-3):249-52. PMID: 12738095 [PubMed - indexed for MEDLINE] | |
| 7: | Kim HS, Begum K, Ogura N, Wataya Y, Nonami Y, Ito T, Masuyama A, Nojima M, McCullough KJ. | Related Articles, Links |
| Antimalarial activity of novel 1,2,5,6-tetraoxacycloalkanes and 1,2,5-trioxacycloalkanes. J Med Chem. 2003 May 8;46(10):1957-61. PMID: 12723958 [PubMed - indexed for MEDLINE] | |
| 8: | Murakami N, Sugimoto M, Kawanishi M, Tamura S, Kim HS, Begum K, Wataya Y, Kobayashi M. | Related Articles, Links |
| New semisynthetic quassinoids with in vivo antimalarial activity. J Med Chem. 2003 Feb 13;46(4):638-41. PMID: 12570385 [PubMed - indexed for MEDLINE] | |
| 9: | Kim HS, Begum K, Ogura N, Wataya Y, Tokuyasu T, Masuyama A, Nojima M, McCullough KJ. | Related Articles, Links |
| Antimalarial activity of yingzhaosu A analogues. J Med Chem. 2002 Oct 10;45(21):4732-6. PMID: 12361400 [PubMed - indexed for MEDLINE] | |
| 10: | Kim HS, Nagai Y, Ono K, Begum K, Wataya Y, Hamada Y, Tsuchiya K, Masuyama A, Nojima M, McCullough KJ. | Related Articles, Links |
| Synthesis and antimalarial activity of novel medium-sized 1,2,4,5-tetraoxacycloalkanes. J Med Chem. 2001 Jul 5;44(14):2357-61. PMID: 11428929 [PubMed - indexed for MEDLINE] | |
ABSTRACT AND PRESENTATION:
Begum K, and Park Y. Characterization of ion transport peptide in Drosophila and Anophelis moqquito. The 54th Annual Meeting Of the Entomological Society of America, December 10-13, 2006. Indianapolis, IN.
Li B, BegumK, and Park Y. Molecular identification of the genes and coding two AKH peptides and N AKH receptor in Tribolium castanium. The 54th Annual Meeting Of the Entomological Society of America, December 10-13, 2006. Indianapolis, IN.
Aikins MJ, Begum K, Schooley D, and Park Y. 2006. The arginine vasopressin-like peptide and the vesipressin receptor in Tribulium castanium (Coleoptera: Tenebrionidae). The 54th Annual Meeting Of the Entomological Society of America, December 10-13, 2006. Indianapolis, IN.
2. Park Y, Kim H, Begum K and Adam M. A novel function of ion transport peptide in Drosophila ecdysis. The 45th Annual Drosophila Research Conference. Washington DC, March 24-28, 2004.
3. Begum K, Kim HS, Okuda Y, Wataya Y, Kimura M and Huruta T. Genomic analysis of mefloquine-resistant Plasmodium falciparum. The 29th Symposium on Nucleic Acids Chemistry. November, 2002, Kyoto, Japan.
4. Begum K, Kim HS, Yohei Okuda, Yukiko Nagai and Yusuke Wataya. Analysis of mefloquine-resistant Plasmodium falciparum. The 72nd Annual Meeting of the Japanese Society of Parasitology, March, 2002,Tokyo, Japan.
5. Begum K, Kim HS, Yohei Okuda, Nagai Y, Wataya Y, Kimura M and Huruta T. Analysis of pfmdr1 gene in mefloquine-resistant Plasmodium falciparum. The 42 Annual Meeting of Japanese Society of Tropical Medicine. September, 2001,Tokyo, Japan.
6. Begum K, Khatun A and D'Silva J.Nematode parasite of elasmobranch fishes in the Bay of Bengal. Annual Conference of Bangladesh Zoological Society,1995.
7. Begum K, Khatun A and D'Silva J. Tetraphyllidean parasites (Cestodes) in shark, skate and ray of the Bay of Bengal. Annual Conference of Bangladesh Zoological Society, 1995.
8. Begum K, Khatun A and D'Silva J. Cestode parasites from elasmobranch fishes in the Bay of Bengal. Annual Council Report of Zoological Society of Bangladesh, 1993.
9. Begum K. Studies on the parasito-fauna of elasmobranch fishes of the Bay of Bengal. Presented in the Department of Zoology, Eden College, University of Dhaka, 1992.
10. Kim HS, Ishizuka I, Begum K, Wataya Y, Hamada Y, Nonami Y, Tokyasu T, Masuyama A and Nojima M. Development of novel antimalarial drugs: Antimalarial effect of endoperoxides. Pharmaceutical Society of Japan. Yokohama, Japan. March, 2000.
11. Kim HS, Ishizuka I, Nagai Y, Ono K, Begum K, Hamada Y, Nonami Y, Tokyasu T, Masuyama A, Nojima M and Wataya Y. Development of novel antimalarial drugs: In vitro and in vivo antimalarial activity of endoperoxides. Japanese Society of Parasitology. Tokyo, Japan. April, 2000.
12. Ono K, Ogura N, Nagai Y, Hamada Y, Nonami Y, Tokyasu T, Masuyama A, Nojima M, Kim HS, Begum K, and Wataya Y. Development of novel antimalarial drugs- Antimalarial effect of endoperoxides.
13. Ono K, Ogura N, Nagai Y, Kim HS , Begum K, Hamada Y, Nonami Y, Tokyasu T, Masuyama A, Nojima M and Wataya Y. The development of novel antimalarial drugs- Antimalarial effect of endoperoxides. Japanese Society of Tropical Medicine and hygiene. Tokyo, Japan. Nov, 2000.
14. Kim HS , Ono K, Ogura N, Nagai Y, Begum K, Hamada Y, Nonami Y, Tokyasu T, Masuyama A, Nojima M and Wataya Y. Antimalarial activity of endoperoxides. Kurashiki, Japan. Oct, 2000.
15. Ono K, Ogura N, Kim HS , Begum K, Hamada Y, Nonami Y, Tokyasu T, Masuyama A, Nojima M and Wataya Y. Development of novel antimalarial drugs- Antimalarial activity of endoperoxides-..Hokkaido, Japan. April, 2001.
16. Ono K, Ogura N, Kim HS , Begum K, Hamada Y, Nonami Y, Tokyasu T, Masuyama A, Nojima M and Wataya Y. Development of novel antimalarial drugs- Antimalarial effect of endoperoxides. Japanese Society of Tropical Proceedings of The Joint Meeting of The 70th Annual Meeting of the Japanese Society of Parasitology. Yamagata, Japan. Apr, 2001.
17. Ono K, Ogura N, Kim HS, Begum K, Hamada Y, Nonami Y, Tokyasu T, Masuyama A, Nojima M and Wataya Y. Development of novel antimalarial drugs- Antimalarial effect of endoperoxides. The 42 Annual Meeting of Japanese Society of Tropical Medicine and hygiene. September, 2001, Tokyo, Japan.
18. Ogura N , Ono K, Kim HS , Begum K, Masuyama A, Nojima M and Wataya Y. Development of novel antimalarial drugs- Antimalarial effect of endoperoxides. The 72st Annual Meeting of the Japanese Society of Parasitology, March, 2002, Tokyo, Japan.
19. Okuda, Y., Begum K, Kim, HS., Y.,Wataya, Y., Kimura, M. and Huruta, T. Analysis of mefloquine-resistant mechanism in Plasmodium falciparum. The 58 Annual Meeting of Japanese Society of Parasitology. Oct, 2002, Ehime, Japan.
20. Kim HS, Okuda Y. Begum K, Nagai Y, Wataya Y, Kimura M and Huruta T. Analysis of pfmdr1 gene in mefloquine-resistant Plasmodium falciparum. Nucleic Acids Research (Supplement No. 1.) 231-232. (2001)
20. Kim HS, Okuda Y. Begum K, Nagai Y, Wataya Y, Kimura M and Huruta T. Analysis of pfmdr1 gene in mefloquine-resistant Plasmodium falciparum. Nucleic Acids Research (Supplement No. 1.) 231-232. (2001)
Over 40 abtracts/presentation in various national and international conferences presented/published.
Reference:
1. Yoonseong Park, PhD, Assistant Professor, Department of Entomology , 123 West Waters, Kansas State University, Manhattan, KS-66506. E-mail: ypark@ksu.edu. Office phone: (785) 532-5763 Web: http://www.oznet.ksu.edu/entomology/faculty/park.htm
2. Professor Y. Wataya, PhD, Faculty of Pharmaceutical Sciences, Okayama University, Tsushima, Okayama-700, Japan. Email: wataya@cc.okayama_u.ac.jp
3. Ming-Shun Chen, PhD, USDA, ARS & Department of Entomology
Waters Hall, Room 21 , Kansas State University,Manhattan, KS 66506, USA.
Tel: 785-532-4719, Fax: 785-532-6167, Email: mchen@oznet.ksu.edu
